I had the same problem and I know I caused it but couldn't figure out how to fix it til now. In Tweak UI there is a place to tell it to activate when over a window. Unchecking it fixed the problem

Ok i was just looking this prolbem up when i got a text & i 4got cells and shit messs stuff up so i moved it away and it stopped xD

Go to control panel click on mouse icon and look for open new page or link when mouse hovers over top it. and make sure the box is unchecked and i think that should fix it that sounds like that is what your problem is.

Yeah I got this too...from what I've read it's a non-malicious(?) software yoke that doesn't get detected by anti virus and all it serves to do is piss people off!!!!

Same problem. I have Dell laptop, Latitude 600. When I mouseover tabs in a menu, the new tab will automatically open, or if I mouseover a box, it will automatically check or uncheck. I'm wondering if it could be a touchpad issue. I've tried all of the above suggested fixes with no success. It's more of an aggravation than anything, but if I mouseover a file and inadvertantly move my hand (pointer) and it happens to me over another file, it will move the first file into the second.

OK are you on a laptop or a desktop computer ?

Lol im such a nut. i never thought to change my mouse out. my left button was shorting out. well i tried restarting my computer again and then unpluged my mouse and pluged it back in and then the left button didn't work at all. then i switch my mouse and it workes just fine. i think that all of you should try that lol. i had my computer since 2005. maybe the hardware is getting old =0.

Ok I had this and I just fixed it. tweakui - mouse- xmouse. fixed it for me.

I found that as I was typing on my laptop my cursor would jump around or the program of the icon under the mouse arrow would engage without my hitting the left touch-pad button.

After closer examination, I noticed during these cursor jumps while I typed the cursor was sent jumping to the location in my desktop window where the mouse arrow was located.

Apparently this is the result of a corrupted driver or a virus designed to annoy.

I'm running XP

Solution:

Right Click on "My Computer" on your desktop
At the top of the window that appears left click on the "Hardware" tab.
Left click on the "Device Manager" button
Look down the tree of Device items and left click on the plus sign (+) to the left of "Mice and other pointing devices"
At this point you, under the "Mice and other pointing devices" heading, you should see one listed item (driver) if you're using just your touch-pad or one mouse.

Right click on that driver name, in my case it's "Snaptics PS/2...".
From the menu that appears when you right click on the mouse driver, choose "Update driver" by left clcking on it.

Follow the update instructions.

That's it. After you've updated your driver, reboot.

Well i had a similar problem that my mouse would automatically select any icon that i hovered over.. and a single click would open it. this option is available to change under folder options: general:

Thanks to jfr34k I had two mice in my System > Device Manager I had already tried deleting the first one (which stopped my mouse from working) quick restart and i was back to the same problem... But i never thought about deleting the second first. After that my mouse and I were fine, I couldn't use my computer it would open stuff and right click all sorts of junk I left it alone to get a drink and by the time i'd come back it'd opened 111tabs on FireFox. Thank you for the help, the problem was caused by OneCare safty scanners Registry Cleaner by-the-way. It started right as that finished and i did it again hoping it would correct the problem... and it made it worse. That being said that's the first problems I've had with Safety Scanner but it is Microsoft